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76697-50-2

  • Product Name:1-AMINO-2-(ISOPROPYLSULPHONYL)BENZENE
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Product Details

Purity:99%

Best Price Pharmaceutical Intermediates 76697-50-2 1-AMINO-2-(ISOPROPYLSULPHONYL)BENZENE

  • Molecular Formula:C9H13NO2S
  • Molecular Weight:199.274
  • Vapor Pressure:5.19E-06mmHg at 25°C 
  • Melting Point:83.0 to 87.0 °C 
  • Refractive Index:1.548 
  • Boiling Point:381.1 °C at 760 mmHg 
  • PKA:-0.79±0.10(Predicted) 
  • Flash Point:184.3 °C 
  • PSA：68.54000 
  • Density:1.194 g/cm3 
  • LogP:3.11290 

1-AMINO-2-(ISOPROPYLSULPHONYL)BENZENE(Cas 76697-50-2) Usage

Uses

2-Aminophenyl Isopropyl Sulfone is a reagent used in the synthesis of potent and selective anaplastic lymphoma kinase (ALK-5) inhibitors, used as an anti-tumor treatment.

InChI:InChI=1/C9H13NO2S/c1-7(2)13(11,12)9-6-4-3-5-8(9)10/h3-7H,10H2,1-2H3

76697-50-2 Relevant articles

CDK inhibitor based on organic arsine as well as preparation method and application of CDK inhibitor

-

, (2021/03/31)

The invention provides a CDK inhibitor b...

CHEMICAL PROCESS FOR PREPARING PYRIMIDINE DERIVATIVES AND INTERMEDIATES THEREOF

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Paragraph 0174-0175; 0176, (2021/05/21)

PROBLEM TO BE SOLVED: To provide a proce...

Fragment-based modification of 2,4-diarylaminopyrimidine derivatives as ALK and ROS1 dual inhibitors to overcome secondary mutants

Chen, Yuxiang,Guo, Ming,Li, Tong,Li, Wei,Wei, Shangfei,Zhai, Xin,Zhao, Tianming,Zhu, Minglin

, (2020/09/01)

In order to explore novel ALK and ROS1 d...

Chemical Process for Preparing Pyrimidine Derivatives and Intermediates Thereof

-

Paragraph 0281; 0283, (2020/02/20)

The present disclosure relates to a meth...

76697-50-2 Process route

2-(isopropylthioether)aniline hydrochloride
861343-73-9

2-(isopropylthioether)aniline hydrochloride

1-amino-2-(isopropylsulphonyl)benzene
76697-50-2

1-amino-2-(isopropylsulphonyl)benzene

Conditions
Conditions Yield
With dihydrogen peroxide; In water; at 25 ℃; Large scale;
84.5%
C<sub>19</sub>H<sub>29</sub>NO<sub>6</sub>S

C19H29NO6S

1-amino-2-(isopropylsulphonyl)benzene
76697-50-2

1-amino-2-(isopropylsulphonyl)benzene

Conditions
Conditions Yield
With trifluoroacetic acid; In dichloromethane; at 0 - 20 ℃; for 12h;
 

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