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Purity:99%
In this study, a series of novel hydroxy...
The present technology is directed to co...
The present invention provides compounds...
The present invention provides novel pyr...
trans-1-chlorocarbonyl-4-(methoxycarbonyl)-cyclohexane
dimethyl zinc(II)
trans-4-acetylcyclohexanecarboxylic acid methyl ester
| Conditions | Yield |
|---|---|
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With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; In toluene; at 0 - 30 ℃; for 3h;
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63% |
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With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; In toluene; at 15 - 20 ℃; for 3h; Cooling with ice;
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trans-4-(methoxycarbonyl)cyclohexanecarboxylic acid
trans-4-acetylcyclohexanecarboxylic acid methyl ester
| Conditions | Yield |
|---|---|
|
Multi-step reaction with 2 steps
1: SOCl2 / 3 h / 50 °C
2: 1.) CuI / 1.) Et2O, THF, 2 h, 2.) Et2O, THF, 30 min
With copper(l) iodide; thionyl chloride;
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Multi-step reaction with 2 steps
1: thionyl chloride
With thionyl chloride;
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Multi-step reaction with 2 steps
1: N,N-dimethyl-formamide; oxalyl dichloride / dichloromethane / 18 h / 0 - 20 °C / Inert atmosphere
2: dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2 / toluene / 3 h / 15 - 20 °C / Cooling with ice
With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; oxalyl dichloride; N,N-dimethyl-formamide; In dichloromethane; toluene;
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Multi-step reaction with 2 steps
1: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 16 h / 20 °C
2: tetrahydrofuran / 1 h / 20 °C
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In tetrahydrofuran; dichloromethane;
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Multi-step reaction with 2 steps
1: thionyl chloride / dichloromethane; N,N-dimethyl-formamide / 16 h / 0 - 25 °C / Inert atmosphere
2: dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2 / toluene / 3 h / 0 - 30 °C
With thionyl chloride; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; In dichloromethane; N,N-dimethyl-formamide; toluene;
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trans-4-(methoxycarbonyl)cyclohexanecarboxylic acid
trans-hexahydroterephthalic acid
dimethyl 1,4-cyclohexanedicarboxylate
trans-1-chlorocarbonyl-4-(methoxycarbonyl)-cyclohexane
4-Isopropenyl-cyclohexanecarboxylic acid methyl ester
4-Isopropenyl-cyclohexanecarboxylic acid
N-[trans-4-(2-hydroxy-1-methylethyl)cyclohexanecarbonyl]-D-phenylalanine