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162427-79-4

  • Product Name:(R)-1-(2-FLUOROPHENYL)ETHANOL
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Product Details

Purity:99%

High Purity (R)-1-(2-FLUOROPHENYL)ETHANOL 162427-79-4 with Best Price

  • Molecular Formula:C8H9 F O
  • Molecular Weight:140.157
  • Vapor Pressure:0.297mmHg at 25°C 
  • Boiling Point:193.1°Cat760mmHg 
  • Flash Point:87.9°C 
  • PSA：20.23000 
  • Density:1.123g/cm3 
  • LogP:1.87900 

(R)-1-(2-FLUOROPHENYL)ETHANOL(Cas 162427-79-4) Usage

Uses

(R)-1-(2-Fluorophenyl)ethanol is a building block used in the synthesis of orally active lysophosphatidic acid receptor-1 antagonists.

InChI:InChI=1/C8H9FO/c1-6(10)7-4-2-3-5-8(7)9/h2-6,10H,1H3/t6-/m1/s1

162427-79-4 Relevant articles

Iron(II) Complexes Containing Chiral Unsymmetrical PNP′ Pincer Ligands: Synthesis and Application in Asymmetric Hydrogenations

Zirakzadeh, Afrooz,Kirchner, Karl,Roller, Alexander,St?ger, Berthold,Widhalm, Michael,Morris, Robert H.

, p. 3781 - 3787 (2016)

Four new chiral PNP′ pincer ligands with...

Short-Mesochannel SBA-15-Supported Chiral 9-Amino Epicinchonine for Asymmetric Transfer Hydrogenation of Aromatic Ketones

Lou, Lan-Lan,Li, Shanshan,Du, Huanling,Zhang, Jiong,Yu, Wenjun,Yu, Kai,Liu, Shuangxi

, p. 1199 - 1207 (2016)

A short-mesochannel SBA-15 material func...

Novel non-metal catalyst for catalyzing asymmetric hydrogenation of ketone and alpha, beta-unsaturated ketone

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Paragraph 0144-0149, (2021/04/26)

The invention discloses a novel non-meta...

C1-Symmetric PNP Ligands for Manganese-Catalyzed Enantioselective Hydrogenation of Ketones: Reaction Scope and Enantioinduction Model

Zeng, Liyao,Yang, Huaxin,Zhao, Menglong,Wen, Jialin,Tucker, James H. R.,Zhang, Xumu

, p. 13794 - 13799 (2020/11/30)

A family of ferrocene-based chiral PNP l...

Efficient Asymmetric Synthesis of Ethyl (S)-4-Chloro-3-hydroxybutyrate Using Alcohol Dehydrogenase SmADH31 with High Tolerance of Substrate and Product in a Monophasic Aqueous System

Chen, Rong,Liu, Qinghai,Wang, Hualei,Wei, Dongzhi,Xie, Youyu,Yang, Zeyu,Ye, Wenjie

, p. 1068 - 1076 (2020/07/06)

Bioreductions catalyzed by alcohol dehyd...

162427-79-4 Process route

1-(2-fluorophenyl)ethanol
445-26-1

1-(2-fluorophenyl)ethanol

2'-Fluoroacetophenone
445-27-2

2'-Fluoroacetophenone

(1S)-1-(2-fluorophenyl)ethanol
171032-87-4

(1S)-1-(2-fluorophenyl)ethanol

(R)-1-(2-fluorophenyl)ethanol
162427-79-4

(R)-1-(2-fluorophenyl)ethanol

Conditions
Conditions Yield
With Arthrobacter atrocyaneus; In N,N-dimethyl-formamide; at 32 ℃; for 48h; Microbiological reaction;
 
1-(2-fluorophenyl)ethanol
445-26-1

1-(2-fluorophenyl)ethanol

2'-Fluoroacetophenone
445-27-2

2'-Fluoroacetophenone

(R)-1-(2-fluorophenyl)ethanol
162427-79-4

(R)-1-(2-fluorophenyl)ethanol

Conditions
Conditions Yield
1-(2-fluorophenyl)ethanol; With C28H36ClMnN2O2; potassium acetate; In dichloromethane; water; for 0.0833333h;
With N-Bromosuccinimide; In dichloromethane; water; at 20 ℃; for 4h; enantioselective reaction; Kinetics;
94 % ee

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