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(S)-1,2,3,4-Tetrahydro-5-methoxy-N-propyl-2-naphthalenamine, also known as (S)-NPT, is a chemical compound that belongs to the family of phenethylamines.
(S)-1,2,3,4-tetrahydro-5-methoxy-N-propyl-naphthalen-2-ammonium (R)-2-(2-chlorophenyl)-2-hydroxyacetate
(S)-(-)-(5-methoxy-1,2,3,4-tetrahydronaphthalen-2-yl)propylamine hydrochloride
Conditions | Yield |
---|---|
With hydrogenchloride; In tetrahydrofuran; water; at 65 ℃; for 0.25h;
|
94% |
With hydrogenchloride; In tetrahydrofuran; water; at 60 - 65 ℃; for 2.25h; Reflux;
|
94% |
(S)-1,2,3,4-tetrahydro-5-methoxy-N-propyl-naphthalen-2-ammonium (S)-2-hydroxy-3-phenylpropionate
(S)-(-)-(5-methoxy-1,2,3,4-tetrahydronaphthalen-2-yl)propylamine hydrochloride
Conditions | Yield |
---|---|
(S)-1,2,3,4-tetrahydro-5-methoxy-N-propyl-naphthalen-2-ammonium (S)-2-hydroxy-3-phenylpropionate; With sodium hydroxide; In 2-methyltetrahydrofuran; water; at 20 ℃;
With hydrogenchloride; In 2-methyltetrahydrofuran; water; at 60 ℃;
|
84% |
(S)-1,2,3,4-tetrahydro-5-methoxy-N-propyl-naphthalen-2-ammonium (S)-2-hydroxy-3-phenylpropionate; With sodium hydroxide; In 2-methyltetrahydrofuran; water; at 20 ℃;
With hydrogenchloride; In 2-methyltetrahydrofuran; water; at 60 ℃;
|
84% |
The CAS number of (S)-NPT is 93601-86-6.
More information of (S)-NPT 93601-86-6 are:
CAS Number |
93601-86-6 |
Density |
1.19g/cm3 at 20℃ |
Vapor Pressure |
0-0Pa at 20-25℃ |
HS CODE |
2932999099 |
European Community (EC) Number | 695-797-0 |
DSSTox Substance ID | DTXSID40647190 |
PSA |
21.26000 |
LogP |
3.74500 |
Synonyms for (S)-NPT 93601-86-6:(2S)-5-Methoxy-N-propyl-1,2,3,4-tetrahydronaphthalen-2-aminhydrochlorid(1:1);CS-M1826;AKOS015901774;Tetrahydro-5-methoxy-N-propyl-2-naphthalenamine hydrochloride.
The chemical formula of (S)-1,2,3,4-Tetrahydro-5-methoxy-N-propyl-2-naphthalenamine hydrochloride is C14H21NO.HCl which containing 14 Carbon atoms,22 Hydrogen atoms,1 Nitrogen atoms and 1 Chlorine atoms,and the molecular weight of (S)-1,2,3,4-Tetrahydro-5-methoxy-N-propyl-2-naphthalenamine hydrochloride is 255.788.
(S)-NPT is a selective serotonin releasing agent (SSRA) and a serotonin-norepinephrine-dopamine releasing agent (SNDRA). (S)-NPT has been studied for its potential use in treating depression, anxiety, and other psychiatric disorders. The safety of (S)-1,2,3,4-Tetrahydro-5-methoxy-N-propyl-2-naphthalenamine, or (S)-NPT, has not been fully established yet. It is a relatively new compound that is still undergoing preclinical and clinical studies to determine its safety and efficacy. However, like with any other research chemical, it is important to handle (S)-NPT with caution and follow appropriate safety protocols when working with it. If you have any concerns about the safety of (S)-NPT, it is recommended that you consult with a qualified professional before using it.
Relevant articles related to (S)-1,2,3,4-Tetrahydro-5-methoxy-N-propyl-2-naphthalenamine hydrochloride:
Article |
Source |
Pharmacological characterization of the selective serotonin releasing agent (S)-NPT: in vitro and in vivo studies in mice. | Rickli, A., et al. Psychopharmacology 237.3 (2020): 819-830. |
Pharmacological profile of the serotonin and norepinephrine releasing agent (S)-NPT: in vitro and in vivo studies in rats. | Luethi, D., et al. European Neuropsychopharmacology 29 (2019): S588-S589. |
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